Acoustofluidic devices based on surface acoustic waves (SAWs) have been widely applied in biomedical research for the manipulation and separation of cells. In this work, we develop an accessible manufacturing process to fabricate an acoustofluidic device consisting of a SAW interdigital transducer (IDT) and a polydimethylsiloxane microchannel. The IDT is manufactured using a flexible printed circuit board pre-patterned with interdigital electrodes that is mechanically coupled with a piezoelectric substrate. A new microchannel moulding technique is realised by 3D printing on glass slides and is demonstrated by constructing the microchannel for the acoustofluidic device. The flexible clamping mechanism, used to construct the device, allows the reconfigurable binding between the IDT and the microchannel. This unique construction makes the acoustofluidic device capable of adjusting the angle between the microchannel and the SAW propagation, without refabrication, via either rotating the IDT or the microchannel. The angle adjustment is demonstrated by setting the polystyrene microsphere aggregation angle to −5, 0, 6, and 15. Acoustic energy density measurements demonstrate the velocity of microsphere aggregation in the device can be accurately controlled by the input power. The manufacturing process has the advantages of reconfigurability and rapid-prototyping to facilitate preparing acoustofluidic devices for wider applications.

基于表面声波 (SAW) 的声流体装置已广泛应用于生物医学研究中，用于细胞的操作和分离。在这项工作中，我们开发了一种易于使用的制造工艺来制造由 SAW 叉指换能器 (IDT) 和聚二甲基硅氧烷微通道组成的声流体装置。IDT 使用柔性印刷电路板制造，该电路板带有与压电基板机械耦合的叉指电极。通过在载玻片上进行 3D 打印实现了一种新的微通道成型技术，并通过构建声流体装置的微通道进行了演示。用于构建设备的灵活夹紧机制允许 IDT 和微通道之间的可重构绑定。这种独特的结构使声流体装置能够通过旋转 IDT 或微通道来调整微通道和 SAW 传播之间的角度，而无需重新制造。通过将聚苯乙烯微球聚集角度设置为 -5、0、6 和 15 来演示角度调整。声能密度测量表明设备中微球聚集的速度可以通过输入功率精确控制。制造过程具有可重构性和快速成型的优点，有助于为更广泛的应用准备声流体装置。通过将聚苯乙烯微球聚集角度设置为 -5、0、6 和 15 来演示角度调整。声能密度测量表明设备中微球聚集的速度可以通过输入功率精确控制。制造过程具有可重构性和快速成型的优点，有助于为更广泛的应用准备声流体装置。通过将聚苯乙烯微球聚集角度设置为 -5、0、6 和 15 来演示角度调整。声能密度测量表明设备中微球聚集的速度可以通过输入功率精确控制。制造过程具有可重构性和快速成型的优点，有助于为更广泛的应用准备声流体装置。