Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular, used by researchers and industrials to design, optimize, understand and create innovative emission tomography systems. In this paper, we reviewed the recent developments that have been proposed to simulate modern detectors and provide a comprehensive report on imaging systems that have been simulated and evaluated in GATE. Additionally, some methodological developments that are not specific for imaging but that can improve detector modeling and provide computation time gains, such as Variance Reduction Techniques and Artificial Intelligence integration, are described and discussed.

GATE 建立在 Geant4 工具包之上，经过 15 多年的合作开发，旨在设计核成像系统的蒙特卡罗模拟。特别是，研究人员和工业界使用它来设计、优化、理解和创建创新的发射断层扫描系统。在本文中，我们回顾了最近提出的模拟现代探测器的发展，并提供了关于在 GATE 中模拟和评估的成像系统的综合报告。此外，还描述和讨论了一些并非专门针对成像但可以改进探测器建模并提供计算时间增益的方法学发展，例如方差减少技术和人工智能集成。