High-intensity focused ultrasound (HIFU) is a novel noninvasive cancer treatment that is expected to be a potential alternative to conventional therapies. In the treatment, the accurate prediction of the ultrasonic heat source prior to therapeutic exposure is important for safety and efficacy. Acoustic radiation force imaging using a short HIFU burst has been proposed as a method for this prediction from the distribution of the tissue displacement. In this study, the effect of the difference in shear modulus on the estimation of the HIFU heat source was experimentally investigated by applying the imaging method to different biological tissues: chicken breast and chicken liver tissues. The result suggested that HIFU radiation force imaging has the potential to determine the HIFU power for appropriate treatment quantitatively from the displacement, even in different tissues with different shear moduli.

高强度聚焦超声 (HIFU) 是一种新型的非侵入性癌症治疗方法，有望成为传统疗法的潜在替代方案。在治疗中，在治疗暴露之前准确预测超声热源对于安全性和有效性很重要。已经提出使用短 HIFU 突发的声辐射力成像作为根据组织位移分布进行预测的一种方法。在这项研究中，通过将成像方法应用于不同的生物组织：鸡胸肉和鸡肝组织，实验研究了剪切模量差异对 HIFU 热源估计的影响。结果表明，HIFU 辐射力成像具有从位移定量确定适当治疗的 HIFU 功率的潜力，