Introduction: There is a dearth of evidence about the effects of Sonas, a multisensory stimulation on people with dementia (PWD). The main aim of this study was to examine the effects of the Sonas program on anxiety and depression in nursing home (NH) residents with dementia. Methods: In all, 120 PWD ≥65 years of age from 6 NHs were included in a randomized control trial and were allocated to 1 of 3 groups for 24 weeks: a Sonas program group (n = 48), a reading group (n = 32), and a control group (n = 40). One hundred and five participants completed follow-up assessments. Anxiety and depression were assessed by the Rating Anxiety in Dementia (RAID) scale and the Cornell Scale for Depression in Dementia (CSDD), respectively. Generalized linear mixed models were estimated to assess trends in the proportion of participants with anxiety (a RAID score ≥11) and depression (a CSDD score ≥10). Results: No significant reduction in anxiety from baseline to follow-up was observed in any of the groups. Participants in the Sonas group showed a significant reduction in depression from baseline to 12 weeks (p = 0.001) and from baseline to 24 weeks (p = 0.009). Conclusion: The Sonas program had no effect on severity of anxiety but a reduction in depressive symptoms was found in PWD.
Dement Geriatr Cogn Disord Extra 2021;11:151–158

中文翻译：

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Sonas 计划对痴呆症疗养院居民焦虑和抑郁的影响：一项为期 6 个月的随机对照试验

简介：缺乏关于 Sonas 效果的证据，Sonas 是一种多感官刺激对痴呆症 (PWD) 患者的影响。本研究的主要目的是检查 Sonas 计划对患有痴呆症的疗养院 (NH) 居民的焦虑和抑郁的影响。方法：总共有 120 名来自 6 个 NH 的 65 岁以上的 PWD 被纳入随机对照试验，并被分配到 3 个组中的 1 个组，持续 24 周：Sonas 程序组（ n = 48）、阅读组（ n = 32) 和一个对照组 ( n= 40）。105 名参与者完成了后续评估。焦虑和抑郁分别通过痴呆焦虑评定量表 (RAID) 和康奈尔痴呆抑郁量表 (CSDD) 进行评估。估计广义线性混合模型以评估焦虑（RAID 评分≥11）和抑郁（CSDD 评分≥10）参与者比例的趋势。结果：在任何组中均未观察到从基线到随访的焦虑显着减少。Sonas 组的参与者表现出从基线到 12 周 ( p = 0.001) 和从基线到 24 周 ( p = 0.009) 的抑郁症显着减少。结论：Sonas 计划对焦虑的严重程度没有影响，但发现 PWD 的抑郁症状有所减轻。
Dement Geriatr Cogn Disord Extra 2021；11:151–158