This article shows the lessons learned from clinical trials of a new neurorehabilitation therapy for cerebro-vascular accident (CVA) patients. The new therapy is based on the combination of a transcranial direct current stimulation (tDCS) strategy, a brain-machine interface (BMI) based on electroencephalographic signals, and a pedaling system. The new therapy was applied during five consecutive days to six CVA patients with motor limitations in their right lower limb that are in the subacute phase. In this article, not only the clinical results are presented, but also the experiences and challenges of performing clinical trials with patients are described, which can be of great interest for future researchers that are planning to evaluate BMIs and tDCS systems with patients.

中文翻译：

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基于 tDCS、BMI 和踏板系统的神经康复治疗临床试验的经验教训


本文展示了从针对脑血管意外 (CVA) 患者的新型神经康复疗法的临床试验中吸取的经验教训。新疗法基于经颅直流电刺激（tDCS）策略、基于脑电图信号的脑机接口（BMI）和踏板系统的组合。新疗法连续五天应用于六名右下肢运动受限且处于亚急性期的 CVA 患者。本文不仅介绍了临床结果，还描述了对患者进行临床试验的经验和挑战，这可能会引起未来计划对患者评估 BMI 和 tDCS 系统的研究人员的极大兴趣。