Candida species are among the most prevalent and abundant members of the gut mycobiota, with Candida albicans (CA) being the most prominent member. CA colonizes numerous mucosal surfaces, most notably the gastrointestinal (GI) and genitourinary tracts. In a healthy host, CA is a pathobiont that exists as a commensal but can become pathogenic if the host’s immune system becomes suppressed. The microbial and/or host factors that dictate CA’s ability to colonize mucosal surfaces and its ability to disseminate remain of great interest. Here, we review the recent advances and insights regarding Candida colonization and dissemination of the mammalian GI tract.

念珠菌属是肠道菌群中最普遍和最丰富的成员之一，其中白色念珠菌(CA) 是最突出的成员。CA 定植于许多粘膜表面，最显着的是胃肠道 (GI) 和泌尿生殖道。在健康的宿主中，CA 是一种共生菌，但如果宿主的免疫系统受到抑制，它就会变得致病。决定 CA 定植黏膜表面的能力及其传播能力的微生物和/或宿主因素仍然引起人们极大的兴趣。在这里，我们回顾了有关念珠菌定植和哺乳动物胃肠道传播的最新进展和见解。