An efficient I₂/TBHP promoted isocyanide insertion cyclization reaction for the synthesis of quinazolines-fused benzoimidazole was reported. The synthesized compounds have a unique potential to use as a selective solvatochromic fluorescence probe for methanol detection from other solvents, especially EtOH. Introducing a simple one-step method and using a more acceptable iodine molecule instead of expensive transition metal catalysts are the most important advantages of this strategy.

中文翻译：

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I ₂ /TBHP 促进异氰化物插入环化反应合成喹唑啉稠合苯并咪唑作为甲醇选择性检测探针

报道了一种有效的 I ₂ /TBHP 促进的异氰化物插入环化反应，用于合成喹唑啉类稠合苯并咪唑。合成的化合物具有独特的潜力，可用作选择性溶剂化显色荧光探针，用于检测其他溶剂（尤其是乙醇）中的甲醇。引入简单的一步法并使用更可接受的碘分子代替昂贵的过渡金属催化剂是该策略最重要的优势。