The brain of a chimpanzee estimated to be 68 years old, the oldest reported so far, has been examined. Pathological analyses revealed the formation of mild tau-positive neuritic clusters and cytoplasmic α-synuclein aggregates, in addition to severe cerebral amyloid angiopathy and diffuse plaques, but no tangle lesions were observed.

中文翻译：

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超龄黑猩猩（Pan troglodytes）大脑中的蛋白质病变

一只估计有 68 岁的黑猩猩的大脑已经过检查，这是迄今为止报道的最古老的黑猩猩。病理分析显示，除了严重的脑淀粉样血管病和弥漫性斑块外，还形成了轻度 tau 阳性神经炎簇和细胞质 α-突触核蛋白聚集体，但未观察到缠结病变。