Objective. To analyze the clinical and polysomnographic characteristics in children with mild OSA and respiratory events terminated predominantly with arousal. Methods. Children aged 3–10 yrs who had mild obstructive sleep apnea (OSA) were enrolled. All children underwent polysomnography, and patients’ data were collected by using sleep-related breathing disorders (SRBD) questionnaire and OSA-18 quality of life questionnaire. Results. In total, five hundred and seventy-seven children were eligible. Children in arousal predominant group were younger and showed a lower rate of male and obesity. Compared with that of the nonarousal predominant group, the total arousal index, arousal index related to respiratory event, the percentage of NREM stage 1 (N1%), the fraction of respiratory events that were hypopnea, and the mean and minimum oxygen saturation in the arousal predominant group were significantly greater. The percentage of NREM stage 3 (N%), index of obstructive, central, mixed apnea, the fraction of respiratory events that were obstructive, and central and mixed apnea were significantly lower in arousal predominant group. Conclusion. Children with mild OSA in the arousal predominant group had specific characteristics, including younger age, lower rate of male and obesity, worse sleep architecture, higher rates of hypopnea events, and better oxygenation. This trial is registered with NCT02447614.

中文翻译：

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轻度 OSA 和呼吸事件主要以觉醒终止的儿童的临床和 PSG 特征

目标。分析轻度 OSA 和呼吸事件主要以觉醒终止的儿童的临床和多导睡眠图特征。方法。招募了患有轻度阻塞性睡眠呼吸暂停 (OSA) 的 3-10 岁儿童。所有儿童均接受多导睡眠监测，并使用睡眠相关呼吸障碍（SRBD）问卷和 OSA-18 生活质量问卷收集患者数据。结果. 总共有五百七十七名儿童符合资格。唤醒优势组的儿童年龄较小，男性和肥胖率较低。与非觉醒优势组相比，总觉醒指数、与呼吸事件相关的觉醒指数、NREM 1期的百分比（N1%）、呼吸不足的呼吸事件比例以及平均和最低氧饱和度唤醒优势组显着更高。觉醒优势组的 NREM 3 期百分比 (N%)、阻塞性、中枢性、混合性呼吸暂停指数、阻塞性呼吸事件的比例以及中枢性和混合性呼吸暂停显着较低。结论. 觉醒为主的轻度 OSA 儿童具有特定特征，包括年龄较小、男性和肥胖率较低、睡眠结构较差、呼吸不足事件发生率较高以及氧合更好。该试验已在 NCT02447614 注册。