Abstract

Purpose

Evaluation of the organ dose in pediatric patients up to 15 years old and Estimation of lifetime attributable risk (LAR) of cancer incidence in pediatric computed tomography procedures.

Materials and methods

Data from 532 patients below 15 years old was collected and they were categorized into four age groups of <1, 1–5, 5–10, and 10–15 years old. NCICT software was used to calculate the organ dose, and LAR of cancer incidence has been estimated according to the BEIR VII report.

Results

The highest median dose in all age groups was related to eye lens (head scan), thyroid (chest scan), and colon (abdomen-pelvic scan). The highest average LAR of cancer incidence was observed for breast cancer and colon cancer following a chest CT scan of the youngest group (<1-year-olds) [68.23 per 100,000] and abdomen-pelvic scans of the oldest group (10- to 15-year-olds) [57.30 per 100,000].

Conclusion

This study shows that the average LAR is higher in females and it decreases with age in both genders. Although CT scan has an indispensable application in diagnosis, the patient dose should be taken into account before any examination specifically in pediatric patients.

中文翻译：

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与儿科医学影像中心流行的 CT 扫描程序相关的终生归因癌症风险

 抽象的

 目的

评估 15 岁以下儿科患者的器官剂量，并估计儿科计算机断层扫描程序中癌症发病率的终生归因风险 (LAR)。

 材料和方法

收集了 532 名 15 岁以下患者的数据，并将他们分为 <1、1-5、5-10 和 10-15 岁四个年龄组。使用NCICT软件计算器官剂量，并根据BEIR VII报告估算癌症发病率LAR。

 结果

所有年龄组中最高的中位剂量与眼晶状体（头部扫描）、甲状腺（胸部扫描）和结肠（腹部-骨盆扫描）有关。在对最年轻组（<1 岁）进行胸部 CT 扫描 [每 100,000 人 68.23 例] 以及对最年长组（10 至15 岁）[每 10 万人中有 57.30 人]。

 结论

这项研究表明，女性的平均 LAR 较高，并且男女均随着年龄的增长而下降。尽管 CT 扫描在诊断中具有不可或缺的应用，但在进行任何检查之前，尤其是针对儿科患者，应考虑患者剂量。