Combined cortisol and melatonin measurements with detailed parameter analysis can assess the circadian rhythms in bipolar disorder patients,Brain and Behavior

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Combined cortisol and melatonin measurements with detailed parameter analysis can assess the circadian rhythms in bipolar disorder patients
Brain and Behavior ( IF 2.6 ) Pub Date : 2021-06-06 , DOI: 10.1002/brb3.2186
Liang Fang _{1,

2} , Quanmei Yu ₃ , Fanfan Yin ₃ , Jiakuai Yu _{2,

4} , Yunfei Zhang ₃ , Yu Zhang _{2,

4} , Daomin Zhu _{1,

2,

4} , Ximing Qin ₃

Affiliation

Bipolar disorder (BD) is a common chronic mental illness. The circadian clock disorder shows a significant correlation with the pathogenesis, phenotype and recurrence of BD. We aim to evaluate non-invasive methods that can comprehensively assess the circadian rhythmicity in BD patients.

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