In rodents, oestrogen reduces food intake centrally via alpha oestrogen receptors (αER). As there was no report about the central roles of oestrogen receptors of alpha and beta, on food intake behaviour in birds, we aimed at this subject. In the first experiment beta oestradiol, a specific beta oestrogen receptor (βER; 0, 2.5, 5,10, 15 and 31 μg) was injected intracerebroventricularly (ICV) to 3-h fasted broilers. The second and third experiments were similar to the first one, but alpha oestradiol, the specific (αER; 2.5, 5 and 10 μg) and MPP hydrochloride, a highly selective antagonist of (αER) (0.1, 1 and 10 μg) were used. Our result showed that alpha oestradiol increased food intake and MPP hydrochloride reversed this effect. This study shows that, similar to rodents, in the avian brain (aER) are involved in food intake behavior, but despite them, their effects are stimulatory.

中文翻译：

---

α 和 β 雌激素受体对食物摄入的禽类中心作用

在啮齿动物中，雌激素通过α雌激素受体（αER）集中减少食物摄入。由于没有关于 α 和 β 雌激素受体对鸟类食物摄入行为的中心作用的报道，我们针对这个主题。在第一个实验中，β 雌二醇是一种特定的 β 雌激素受体（βER；0、2.5、5、10、15 和 31 μg）被脑室内 (ICV) 注射到禁食 3 小时的肉鸡。第二个和第三个实验与第一个相似，但使用了α雌二醇，特异性（αER；2.5、5和10μg）和MPP盐酸盐，一种（αER）的高选择性拮抗剂（0.1、1和10μg） . 我们的结果表明，α 雌二醇增加了食物摄入，而 MPP 盐酸盐逆转了这种作用。这项研究表明，与啮齿动物相似，在鸟类大脑（aER）中参与食物摄入行为，