Over the past 15 years, mechanochemistry has developed into a powerful tool for the synthesis of molecules and materials while avoiding the consumption of bulk solvents. With tailored instruments and well-understood milling/grinding techniques, experimentalists are now tackling synthetic problems of increasing complexity, such as implementing the use of a catalyst to enable specific chemical pathways and control reaction selectivity. This Opinion provides a snapshot of the current state of affairs in the field, highlighting recent examples that employ metal-based catalysts under mechanochemical conditions, as well as the context and specific features of the underlying methods.

在过去的 15 年中，机械化学已发展成为合成分子和材料同时避免消耗大量溶剂的有力工具。借助量身定制的仪器和广为人知的研磨/研磨技术，实验人员现在正在解决日益复杂的合成问题，例如使用催化剂来实现特定的化学途径和控制反应选择性。该意见提供了该领域当前状况的快照，重点介绍了在机械化学条件下使用金属基催化剂的最新例子，以及基本方法的背景和具体特征。