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Facile synthesis of ZnO nanoparticles by Actinidia deliciosa fruit peel extract: Bactericidal, anticancer and detoxification properties
Environmental Research ( IF 7.7 ) Pub Date : 2021-06-04 , DOI: 10.1016/j.envres.2021.111433
Jie Li 1 , Yi Li 1 , Haisuo Wu 2 , Saraschandra Naraginti 3 , Yunbo Wu 2
Affiliation  

Synthesis of nanoparticles by eco-friendly method pulled an extensive concern worldwide due its biocompatibility and wide range of applications as catalysts, microbicidal agents, cancer treatment, sensors etc. Though different chemical methods available for preparation of ZnO nanoparticles, synthesis by utilizing plant material is an excellent substitute and green method as well. The present study describes preparation of ZnO nanoparticles by low-cost green synthetic way using (kiwi) fruit peel extract and its excellent biological and catalytic properties. The synthesized nanoparticles were well characterized by UV visible spectroscopy, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM) and Energy-dispersive X-ray spectroscopy (EDAX). The bactericidal activity of the ZnO nanoparticles was determined by using (), while mechanism of cell death was studied by SEM images. Superior anticancer activity was also observed in inhibiting the colon cancer cells (HCT116) by the ZnO nanoparticles. In addition, ZnO nanoparticles showed efficient photocatalytic activity towards degradation of -bromophenol, about 96.3% within 120 min. Furthermore, phytotoxicity of the intermediate products was analyzed using Vigna radiata (V. radiata) as a model plant. About 8.0% of germination index (GI) was observed in pure p-BP while it increased to 82.3%, and exhibited that the detoxification of p-BP was attained after 120 min of degradation. Thus, the present study demonstrates ZnO nanoparticles prepared from simple, rapid, inexpensive, eco-friendly and efficient green method gives alternative root for biomedicine and wastewater treatment technologies.

中文翻译:


利用美味猕猴桃果皮提取物轻松合成氧化锌纳米粒子:杀菌、抗癌和解毒特性



采用环保方法合成纳米颗粒因其生物相容性以及在催化剂、杀菌剂、癌症治疗、传感器等方面的广泛应用而受到世界范围内的广泛关注。虽然可用于制备ZnO纳米颗粒的化学方法不同,但利用植物材料合成是最有效的方法。也是一种很好的替代品和绿色方法。本研究描述了利用猕猴桃果皮提取物通过低成本绿色合成方式制备氧化锌纳米颗粒及其优异的生物和催化性能。合成的纳米粒子通过紫外可见光谱、X射线衍射(XRD)、傅里叶变换红外光谱(FTIR)、扫描电子显微镜(SEM)、透射电子显微镜(TEM)和能量色散X射线光谱(EDAX)进行了表征。 )。使用()测定ZnO纳米颗粒的杀菌活性,同时通过SEM图像研究细胞死亡机制。 ZnO 纳米粒子在抑制结肠癌细胞 (HCT116) 方面也观察到优异的抗癌活性。此外,ZnO 纳米颗粒对溴苯酚的降解表现出高效的光催化活性,120 分钟内降解率约为 96.3%。此外,以辐射绿豆(V. radiata)为模型植物,分析了中间产物的植物毒性。纯 p-BP 的发芽指数 (GI) 约为 8.0%,而它增加到 82.3%,表明降解 120 分钟后 p-BP 已达到解毒效果。因此,本研究表明,通过简单、快速、廉价、环保和高效的绿色方法制备的ZnO纳米颗粒为生物医学和废水处理技术提供了替代根源。
更新日期:2021-06-04
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