Background and objective

This study aims to evaluate clinical and radiological findings and treatment outcomes of the patients with PIBO.

Methods

One hundred fourteen children were enrolled. Initial demographic and clinical findings were evaluated. Pre- and post-treatment clinical and radiological findings were compared.

Results

The median age of the patients at initial pulmonary injury was 7,2 months, the median age at diagnosis was 17.5 months. Persistent wheezing was the most common complaint. Thirty-five patients had mechanical ventilation history. 82,5% of patients had clinical improvement. Bronchiectasis, atelectasis, hyperinflation and air trapping in HRCT improved significantly with treatment. Post-treatment Bhalla scores decreased from 8.3 to 6.5 (p= 0,001). Improvement was observed in radiological and clinical findings after treatment.

Conclusions

This study is one of the largest studies in the literature and one of the few studies that evaluate clinical and radiological outcomes of patients with PIBO.

中文翻译：

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儿童感染后闭塞性细支气管炎：临床和放射学评估及长期结果

背景和目标

本研究旨在评估 PIBO 患者的临床和放射学发现以及治疗结果。

方法

一百一十四个孩子被录取了。评估了最初的人口统计学和临床​​发现。比较治疗前后的临床和放射学结果。

结果

初始肺损伤患者的中位年龄为 7.2 个月，诊断时的中位年龄为 17.5 个月。持续喘息是最常见的主诉。35 名患者有机械通气史。82.5% 的患者有临床改善。HRCT 中的支气管扩张、肺不张、过度充气和空气滞留随着治疗得到显着改善。治疗后 Bhalla 评分从 8.3 下降到 6.5 (p= 0,001)。治疗后观察到放射学和临床发现的改善。

结论

这项研究是文献中最大的研究之一，也是为数不多的评估 PIBO 患者临床和放射学结果的研究之一。