3-(Hetero)arylmethyl derivatives of imidazo[1,2-a]pyridine have been synthesized by a novel one-pot method consisting of the Sonogashira coupling of tert-butyl prop-2-yn-1-yl(pyridin-2-yl)carbamate with different substituted (hetero)aryl bromides and cyclization of the in situ obtained intermediate substituted (hetero)aryl acetylene derivatives.

中文翻译：

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银辅助钯催化一锅法合成咪唑并[1,2-a]吡啶的3-（杂）芳甲基衍生物

咪唑并[1,2- a ]吡啶的3-（杂）芳甲基衍生物已通过一种新型的一锅法合成，该方法由叔丁基丙-2-yn-1-基（吡啶-2-）的Sonogashira偶联组成。基)氨基甲酸酯与不同的取代(杂)芳基溴化物和原位环化得到中间体取代的(杂)芳基乙炔衍生物。