Background. It is well known that cancer patients more seldom have a psychiatric disorder than noncancer patients with chronic pain. Conversely, earlier studies have suggested that, at the psychiatric level, long-term cancer survivors (LCSs) have more in common with noncancer patients affected by chronic pain. Materials and Methods. We investigated 89 cancer patients with acute pain (Acute Cancer Pain Patients, ACPPs) treated at a university outpatient chemotherapy department and compared these with 61 LCSs (living >5 yr after the first diagnosis) admitted by general practitioners for the treatment of noncancer pain. Upon administration, each patient was psychiatrically assessed by a liaison-psychiatrist conducting a semistructured interview. In a second step, we compared the LCS patients with hitherto treated noncancer patients suffering from chronic pain and ACPPs with data published by Derogatis in 1983. Results. In a comparison of LCSs with ACPPs, LCSs have more patients with brain organic disorders and more addictions. The largest cancer group within the LCSs is patients with urogenital (Uro) cancer (44.3%), while within the ACPPs, these are patients with cancer of the gastrointestinal (GI) tract (ACPP-GI, 57.2%). As far as the distribution of mental disorders is concerned, long-term cancer survivors show some similarities to noncancer patients. The data of ACPPs are similar to those of cancer patients, published by Derogatis. Discussion. The higher values of addiction and brain organic disorders, in particular, and the slight differences for psychic disorders in general of LCSs vs. ACPPs may result from the different cancer types and a longer survival time for urogenital tract cancer compared to GI cancer. In an additional examination, we compared patients with acute cancer of the GI tract (ACPP-GI, n = 50) with those of the urogenital tract (ACPP-Uro, n = 43). ACPP-Uro had the lowest percentage of patients with psychiatric disorders in general (ACPP-Uro 37.2%, ACPP-GI 50.0%, all LCSs 65.6%, and LCS-Uro 74.1%) and addiction, in particular (ACPP-Uro 2.3%, ACPP-GI 4.0%, and LCSs 13.1%). Conclusion. Cancer patients can develop a process of chronification with an increase in the prevalence of mental disorders. For urogenital cancer, an increase in the probability to develop mental disorders is a function of time.

中文翻译：

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癌症疼痛患者的精神障碍发病率随时间增加：来自回顾性队列研究的数据

背景。众所周知，与患有慢性疼痛的非癌症患者相比，癌症患者很少患有精神疾病。相反，早期的研究表明，在精神病学层面，长期癌症幸存者 (LCS) 与受慢性疼痛影响的非癌症患者有更多共同点。材料和方法. 我们调查了 89 名在大学门诊化疗部门接受治疗的急性疼痛癌症患者（Acute Cancer Painpatients，ACPPs），并将这些患者与 61 名 LCS（首次诊断后存活 5 年以上）由全科医生接受治疗非癌性疼痛进行比较。给药后，每位患者均由精神科联络医师进行半结构化访谈进行精神评估。在第二个步骤中，我们比较了LCS患者的慢性疼痛和痛苦ACPPs与Derogatis于1983年公布的数据迄今治疗非癌症患者的结果. 在 LCS 与 ACPP 的比较中，LCS 有更多的脑器质性疾病患者和更多的成瘾患者。LCS 中最大的癌症组是泌尿生殖 (Uro) 癌症患者 (44.3%)，而在 ACPP 中，这些是胃肠 (GI) 道癌症患者 (ACPP-GI，57.2%)。就精神障碍的分布而言，长期癌症幸存者与非癌症患者表现出一些相似之处。ACPPs 的数据与 Derogatis 发表的癌症患者的数据相似。讨论. 特别是成瘾和脑器质性疾病的较高值，以及 LCS 与 ACPP 的一般精神障碍的轻微差异可能是由于不同的癌症类型以及与 GI 癌症相比泌尿生殖道癌症的更长生存时间。在另一项检查中，我们将胃肠道急性癌症患者 (ACPP-GI, n  = 50) 与泌尿生殖道癌症患者(ACPP-Uro, n  = 43) 进行了比较。ACPP-Uro 的精神障碍患者比例最低（ACPP-Uro 37.2%，ACPP-GI 50.0%，所有 LCS 65.6%，LCS-Uro 74.1%）和成瘾，特别是（ACPP-Uro 2.3%） 、ACPP-GI 4.0% 和 LCS 13.1%）。结论. 随着精神障碍患病率的增加，癌症患者可能会发展出一个慢性化的过程。对于泌尿生殖系统癌症，发生精神障碍的可能性增加是时间的函数。