Interfacing non-enzymatic catalysis with cellular metabolism is emerging as a powerful approach to produce a range of high value small molecules and polymers. In this review, we highlight recent examples from this promising young field. Specifically, we discuss demonstrations of living cells mediating redox processes for biopolymer production, interfacing solar-light driven chemistry with microbial metabolism, and intra- and extracellular non-enzymatic catalysis to generate high value molecules. This review highlights the vast potential of this nascent field to bridge the two disciplines of synthetic chemistry and synthetic biology for a sustainable chemical industry.

中文翻译：

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非酶催化与活微生物的接口

将非酶催化与细胞代谢相结合正在成为生产一系列高价值小分子和聚合物的有力方法。在这篇评论中，我们重点介绍了这个有前途的年轻领域的最新例子。具体来说，我们讨论了活细胞介导生物聚合物生产的氧化还原过程、将太阳光驱动化学与微生物代谢相结合以及细胞内和细胞外非酶催化产生高价值分子的示范。这篇综述强调了这一新兴领域在连接合成化学和合成生物学这两个学科以实现可持续化学工业方面的巨大潜力。