High-resolution three-dimensional (3D) post-contrast imaging of the brain is essential for comprehensive evaluation of inflammatory, neoplastic, and neurovascular diseases of the brain. 3D T1-weighted spin-echo-based sequences offer increased sensitivity for the detection of enhancing lesions but are relatively prolonged examinations. We evaluated whether a highly accelerated Wave-controlled aliasing in parallel imaging (Wave-CAIPI) post-contrast 3D T1-sampling perfection with application-optimized contrasts using different flip angle evolutions (T1-SPACE) sequence (Wave-T1-SPACE) was noninferior to the standard high-resolution 3D T1-SPACE sequence for visualizing enhancing lesions with comparable diagnostic quality.

中文翻译：

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MRI 高加速波-CAIPI T1-SPACE 与标准 T1-SPACE 在 3T 检测脑钆增强病变

大脑的高分辨率三维 (3D) 对比后成像对于全面评估大脑的炎症、肿瘤和神经血管疾病至关重要。3D T1 加权自旋回波序列为检测增强病变提供了更高的灵敏度，但检查时间相对较长。我们评估了并行成像中高度加速的波控制混叠 (Wave-CAIPI) 对比后 3D T1 采样完美与使用不同翻转角演变 (T1-SPACE) 序列 (Wave-T1-SPACE) 的应用优化对比度不劣于标准高分辨率 3D T1-SPACE 序列，用于可视化具有可比诊断质量的增强病变。