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Diabetes following acute pancreatitis
The Lancet Gastroenterology & Hepatology ( IF 30.9 ) Pub Date : 2021-06-03 , DOI: 10.1016/s2468-1253(21)00019-4
Phil A Hart 1 , David Bradley 2 , Darwin L Conwell 1 , Kathleen Dungan 2 , Somashekar G Krishna 1 , Kathleen Wyne 2 , Melena D Bellin 3 , Dhiraj Yadav 4 , Dana K Andersen 5 , Jose Serrano 5 , Georgios I Papachristou 1
Affiliation  

Diabetes represents a group of diseases involving persistent hyperglycaemia. Exocrine disorders of the pancreas are increasingly recognised to cause or precede the onset of diabetes, which in this context is referred to as pancreatogenic or type 3c diabetes. Diabetes, as a sequela of acute pancreatitis, is observed across the spectrum of severity in acute pancreatitis and can be associated with other clinical complications. The pathophysiology of acute pancreatitis-related diabetes is poorly understood, and observations suggest that it is probably multifactorial. In this Review, we discuss the epidemiology, pathophysiology, and management considerations of diabetes following acute pancreatitis, and highlight knowledge gaps in this topic.



中文翻译:


急性胰腺炎后糖尿病



糖尿病代表一组涉及持续高血糖的疾病。越来越多的人认识到胰腺的外分泌疾病会导致糖尿病或先于糖尿病的发作,在这种情况下,糖尿病被称为胰源性糖尿病或 3c 型糖尿病。糖尿病作为急性胰腺炎的后遗症,在急性胰腺炎的严重程度范围内均可观察到,并且可能与其他临床并发症相关。对急性胰腺炎相关糖尿病的病理生理学知之甚少,观察表明它可能是多因素的。在这篇综述中,我们讨论了急性胰腺炎后糖尿病的流行病学、病理生理学和治疗注意事项,并强调了该主题的知识差距。

更新日期:2021-07-09
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