There is an important need to develop a transcatheter/trans-septal-like model which will allow deliverability of mitral valve devices at the right angulation and height above the mitral annulus similar to the human patient. A ministernotomy allowing for TEE probe to be introduced transpericardially was performed in seven animals. In three, a standard trans-septal approach was used to attempt to deliver a device to the level of the mitral plane with a human delivery system. In four cases, a Dacron tube was connected to the RPV and the device introduced to the LA. Under TEE equivalent imaging, the device was then successfully steered to the mitral plane in all cases, having failed in all trans-septal attempts. A combination of transpericardial echocardiographic imaging (TPE) and RPV approach to the LA facilitated successful human-like mitral valve device implantation.

非常需要开发一种经导管/经间隔样模型，该模型将允许二尖瓣装置在与人类患者相似的二尖瓣环上方的正确角度和高度处的输送能力。在七只动物中进行了允许经心包引入 TEE 探针的部长切开术。在三个中，使用标准的经中隔方法尝试通过人类输送系统将设备输送到二尖瓣平面的水平。在四个案例中，将涤纶管连接到 RPV 并将设备引入 LA。在 TEE 等效成像下，该装置在所有情况下均成功转向二尖瓣平面，但在所有跨间隔尝试中均失败。