Fimbrin, a regulator of actin cytoskeletal dynamics that participates in numerous physiological and biochemical processes, controls multiple developmental processes in a variety of tissues and cell types. However, the role of fimbrin in pathogen defense of wheat and the mechanisms have not been well studied. Here, we investigated that the expression of TaFIM1 gene of wheat was significantly induced in response to avirulent race of Puccinia striiformis f. sp. tritici (Pst) and silencing of TaFIM1 by virus-induced gene silencing method. The results show that silencing of TaFIM1 resulted in a reduction of resistance against the stripe rust indicated by both phenotypes and a histological examination of Pst growth. Additionally, the expression level of TaFIM1 gene was up-regulated under abiotic stresses. These findings suggest that TaFIM1 functions as a positive regulator of pathogen resistance of wheat plants and response to abiotic stress. Our work may show new light on understanding the roles of fimbrin in wheat.

Fimbrin 是参与众多生理和生化过程的肌动蛋白细胞骨架动力学的调节剂，控制着多种组织和细胞类型的多种发育过程。然而，纤维蛋白在小麦病原防御中的作用及其机制尚未得到很好的研究。在这里，我们研究了小麦TaFIM1基因的表达在响应Puccinia striiformis f 的无毒小种时被显着诱导。sp. 通过病毒诱导的基因沉默方法抑制小麦( Pst ) 和TaFIM1的沉默。结果表明TaFIM1 的沉默导致对条锈病的抗性降低，由表型和Pst生长的组织学检查表明。此外，TaFIM1基因的表达水平在非生物胁迫下上调。这些发现表明TaFIM1作为小麦植物病原体抗性和对非生物胁迫响应的正调节因子。我们的工作可能会为理解纤维蛋白在小麦中的作用提供新的线索。