Objectives: This study was conducted to assess the impact of oral mucositis on nutrition and performance status in pediatric cancer patients treated by chemotherapy.

Data Sources: A total of 46 children were followed for mucositis episode, and their mean Oral Assessment Guide score was 20.2. Main concomitant disorders were hematological changes (86.9%), loss of appetite (60.7%), vomiting (28.3%), and diarrhea (10.9%).

Conclusion: Anthropometric changes were highlighted by a decrease in body mass index (P = .03) and a decrease of Waterlow score (P = .007). Most patients had a low Lansky Play Performance Scale (LPPS) ≤40 (86.9%). High mucositis grades (P = .007) and long hospital stay (P = .005) were associated with a significant reduction in Lansky Play Performance Scale. Patient's follow-up showed need for hospitalization (84.8%), delay in chemotherapy treatment (71.7%), use of opioides (34.8%), and use of parenteral nutrition (26.1%). Death occurred in 10.9% of the cases.

Implications for Nursing Practice: These findings illustrate the impact of mucositis on nutrition and performance status in children undergoing chemotherapy, which considerable affected their outcome.

目的：本研究旨在评估口腔粘膜炎对接受化疗的儿童癌症患者的营养和体能状态的影响。

数据来源：共有 46 名儿童因粘膜炎发作而被随访，他们的平均口腔评估指南得分为 20.2。主要伴随疾病为血液学改变（86.9%）、食欲不振（60.7%）、呕吐（28.3%）和腹泻（10.9%）。

结论：人体质量指数的降低 ( P  = .03) 和 Waterlow 评分的降低 ( P  = .007)突出了人体测量学的变化。大多数患者的兰斯基游戏表现量表 (LPPS) ≤ 40 (86.9%)。高黏膜炎等级 ( P  = .007) 和住院时间长 ( P  = .005) 与 Lansky 游戏表现量表的显着降低有关。患者的随访显示需要住院 (84.8%)、延迟化疗 (71.7%)、使用阿片类药物 (34.8%) 和使用肠外营养 (26.1%)。死亡发生率为 10.9%。

对护理实践的影响：这些发现说明了粘膜炎对接受化疗的儿童的营养和体能状态的影响，这对他们的结果产生了相当大的影响。