Guillain-Barré Syndrome (GBS) is a group of acute inflammatory disorders that share a clinical presentation of progressive polyradiculo-neuropathy. Data on GBS in the Middle East and Lebanon are scarce; hence, we explored the characteristics of patients presenting with GBS to a tertiary care center in Beirut, Lebanon. This was a single-centered retrospective study over a 12-year period. We reviewed the charts of patients presenting with GBS to the American University of Beirut medical center and examined their presentation, management and outcome. 61 patients were included, with the majority being males. 59% of the patients reported an infection prior to admission. 77% had sensory and motor symptoms and 69% were diagnosed with acute inflammatory demyelinating polyneuropathy (AIDP). 57% of patients had initial symptoms in the lower extremities, 25% experienced cranial neuropathies, and 26% complained of pain. 77% were managed by intravenous immunoglobulin with a median hospital stay of 6.5 days. AIDP was noted to be the most prevalent GBS variant in Lebanon. More than 50% had an unfavorable outcome at discharge, which raises the need for better treatment and management approaches.

吉兰-巴雷综合征 (GBS) 是一组急性炎症性疾病，具有进行性多发性神经根神经病的临床表现。中东和黎巴嫩的 GBS 数据很少；因此，我们探讨了在黎巴嫩贝鲁特的三级医疗中心就诊的 GBS 患者的特征。这是一项为期 12 年的单中心回顾性研究。我们回顾了就诊于贝鲁特美国大学医学中心的 GBS 患者的图表，并检查了他们的表现、治疗和结果。包括 61 名患者，其中大多数为男性。59% 的患者在入院前报告了感染。77% 有感觉和运动症状，69% 被诊断为急性炎性脱髓鞘性多发性神经病 (AIDP)。57% 的患者最初出现下肢症状，25% 的人经历过颅神经病变，26% 的人抱怨疼痛。77% 的患者接受静脉注射免疫球蛋白治疗，中位住院时间为 6.5 天。AIDP 被认为是黎巴嫩最流行的 GBS 变体。超过 50% 的患者出院时结果不佳，这就需要更好的治疗和管理方法。