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Rigosertib inhibits MEK1–ERK pathway and alleviates lipopolysaccharide-induced sepsis
Immunity, Inflammation and Disease ( IF 3.1 ) Pub Date : 2021-06-01 , DOI: 10.1002/iid3.458
Yin Wang 1 , Pengfei Du 1 , Donghui Jiang 1
Affiliation  

Here, by using the lipopolysaccharide (LPS)-induced mice sepsis model, we treated septic wild-type (WT) mice or MEK1DD mice with rigosertib to evaluate its prospective effects on sepsis.

中文翻译:

Rigosertib 抑制 MEK1-ERK 通路并减轻脂多糖诱导的败血症

在这里,通过使用脂多糖 (LPS) 诱导的小鼠败血症模型,我们用 rigosertib治疗败血症野生型 (WT) 小鼠或 MEK1 DD小鼠,以评估其对败血症的预期效果。
更新日期:2021-08-07
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