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Antimicrobial and Free Radical Scavenging Activities of Cellulose/Silver-Nanocomposites with In Situ Generated Silver Nanoparticles Using Cissampelos Pareira Leaf Extract
Journal of Cluster Science ( IF 2.7 ) Pub Date : 2021-06-01 , DOI: 10.1007/s10876-021-02097-2
Chinnadurai Shanmugam , Ganarajan Sivasubramanian , Poongavanam Govindhan , Parthasarathi Bera , Krishnan Baskaran , Veembil Ramachandra Iyer Parameswaran

In this study, silver nanoparticles (AgNPs) were in situ generated on the surface of cellulose matrix using leaf extract of cissampelos pareira (LCP) by environmentally benign green synthesis. The morphological and structural properties of synthesized cellulose silver nanocomposites (Cel/LCP/Ag-NCs) were characterized by different spectral studies such as UV–visible spectroscopy, SEM, TEM, FT-IR, AFM, DRS, PL, Lifetime, XPS and XRD. Silver nanoparticles were obtained in the cellulose matrix with an average size of 34.26 nm and with antioxidant activity which has been evaluated by ABTS (70.34% at 100 µg/mL) and DPPH (81.65% at 100 µg/mL) methods. The antimicrobial properties of cellulose, Cel/LCP, Cel/LCP (10 mM, 30 mM and 50 mM AgNO3), tested on 13 microorganisms were determined using disk diffusion method. The most effective nanocomposites (Cel/LCP/10, 30 and 50 mM AgNO3), Cel/LCP/50 mM AgNO3 afforded the best antimicrobial properties because increasing the concentration of AgNO3 solution, the zone of inhibition also increased. The prepared cellulose silver nanocomposites synthesized by leaf extract of cissampelos pareira shows the potential to be applied in the future development of therapeutics and biomedical applications.



中文翻译:

使用 Cissampelos Pareira 叶提取物原位生成银纳米颗粒的纤维素/银纳米复合材料的抗菌和自由基清除活性

在这项研究中,银纳米粒子 (AgNPs ) 通过环境良性绿色合成,使用cissampelos pareira (LCP) 的叶提取物在纤维素基质表面原位生成。合成的纤维素银纳米复合材料(Cel/LCP/Ag-NCs)的形态和结构特性通过不同的光谱研究进行表征,如紫外-可见光谱、SEM、TEM、FT-IR、AFM、DRS、PL、Lifetime、XPS和XRD。银纳米颗粒在纤维素基质中获得,平均尺寸为 34.26 nm,具有抗氧化活性,经 ABTS(100 µg/mL 时为 70.34%)和 DPPH(100 µg/mL 时为 81.65%)方法评估。纤维素、Cel/LCP、Cel/LCP(10 mM、30 mM 和 50 mM AgNO 3),使用圆盘扩散法测定了 13 种微生物。最有效的纳米复合材料(Cel/LCP/10、30 和 50 mM AgNO 3)Cel/LCP/50 mM AgNO 3提供了最好的抗菌性能,因为增加 AgNO 3溶液的浓度,抑菌圈也增加了。由cissampelos pareira的叶提取物合成的纤维素银纳米复合材料显示出在未来治疗学和生物医学应用发展中的应用潜力。

更新日期:2021-06-01
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