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Post-traumatic exogenous endophthalmitis caused by Nocardia farcinica
Journal of Ophthalmic Inflammation and Infection Pub Date : 2021-06-01 , DOI: 10.1186/s12348-021-00245-3
Marie Česká Burdová 1 , Kateřina Donátová 1 , Gabriela Mahelková 1, 2 , Vanda Chrenková 3 , Dagmar Dotřelová 1
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A case report of post-traumatic exogenous endophthalmitis caused by Nocardia farcinica, including treatment procedures, microbiology examination, and systemic medications. A 23-year-old male suffered a penetrating corneal injury that was treated with sutures. On the thirteenth day after the final suture was removed, an anterior uveitis developed and progressed to whitish, plump, nodular, and tufted exudates within the anterior chamber over the next 10 days; this led to an indication for intraocular surgery. Anterior chamber lavage and resection of solid fibrinous exudates (using a vitrectomy knife) for a complete microbiological examination were performed. Nocardia farcinica was identified. Systemic medications were chosen according to sensitivity, and a fixed combination of sulfamethoxazole 400 mg/trimethoprim 80 mg was administered long-term (months). In this case, accurate, early detection of an atypical infectious agent and determination of its sensitivity to antibiotic treatment enabled effective treatment that achieved the best functional and anatomical results under the circumstances.

中文翻译:

诺卡氏菌引起的外源性眼内炎

一例由诺卡氏菌引起的创伤后外源性眼内炎病例报告,包括治疗程序、微生物学检查和全身用药。一名 23 岁的男性患有穿透性角膜损伤,接受了缝合治疗。在最后缝合线拆除后的第 13 天,前葡萄膜炎发生并在接下来的 10 天内进展为前房内发白、丰满、结节状和簇状渗出物;这导致了眼内手术的适应症。进行前房灌洗和固体纤维蛋白渗出物切除(使用玻璃体切割刀)以进行完整的微生物学检查。确定了诺卡氏菌。根据敏感性选择全身药物,和磺胺甲恶唑 400 mg/甲氧苄啶 80 mg 的固定组合长期(数月)给药。在这种情况下,准确、早期检测非典型感染原并确定其对抗生素治疗的敏感性,可以进行有效治疗,在这种情况下实现最佳功能和解剖学结果。
更新日期:2021-06-01
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