Dacryoadenitis is an inflammation of the lacrimal gland that may have various etiologies with similar presentations. Despite more recent elucidation of specific causes, the management has remained largely unchanged. Hence, the condition remains under biopsied with the rationale that empirical treatment with corticosteroids is effective for many of the causes. Dacryoadenitis, however, dacryoadenitis can be the presenting sign of an undiagnosed systemic disease and a mimick for lymphoma; hence, tissue diagnosis and systemic investigations play a vital role. A significant proportion of dacryoadenitis has a specific etiology, and IgG4-related dacryoadenitis is more frequently identified as a cause. We summarize the different types of immune-mediated dacryoadenitis, their clinical findings, histopathology, management, and prognosis. We have also highlighted and formulated practice guidelines for diagnosis and effective treatment based on the underlying systemic disease.

泪腺炎是泪腺的炎症，可能有多种病因和相似的表现。尽管最近阐明了具体原因，但管理层基本保持不变。因此，根据皮质类固醇的经验性治疗对许多原因有效的基本原理，该病症仍在活检中。泪腺炎，然而，泪腺炎可能是一种未确诊的全身性疾病的表现征兆，也可能是淋巴瘤的表现；因此，组织诊断和系统检查起着至关重要的作用。很大一部分泪腺炎具有特定的病因，IgG4 相关性泪腺炎更常被确定为病因。我们总结了不同类型的免疫介导的泪腺炎、它们的临床表现、组织病理学、治疗和预后。