Block copolymers are well recognized as excellent nanotools for delivering hydrophobic drugs. The formulation of such delivery nanoparticles requires robust characterization and clarification of the critical quality attributes correlating with the safety and efficacy of the drug before applying to regulatory authorities for approval. Static solution scattering from block copolymers is one such technique. This paper first outlines the theoretical background and current models for analyzing this scattering and then presents an overview of our recent studies on block copolymers.

中文翻译：

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通过溶液静态散射技术表征用于纳米药物的嵌段共聚物胶束

嵌段共聚物被公认为用于递送疏水性药物的优良纳米工具。在向监管机构申请批准之前，此类递送纳米颗粒的配方需要对与药物安全性和有效性相关的关键质量属性进行可靠的表征和澄清。来自嵌段共聚物的静态溶液散射就是这样一种技术。本文首先概述了分析这种散射的理论背景和当前模型，然后概述了我们最近对嵌段共聚物的研究。