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PI3Kα targeting, nipping pancreatic cancer evolution in the bud
EMBO Molecular Medicine ( IF 9.0 ) Pub Date : 2021-05-31 , DOI: 10.15252/emmm.202114362
Glancis Luzeena Raja Arul 1, 2 , Martin E Fernandez-Zapico 1
Affiliation  

Thibault et al (2021) elucidate key signalling events mediating metastatic evolution in pancreatic ductal adenocarcinoma (PDAC) by demonstrating a role of PI3Kα in the regulation of macro-metastatic disease and a corresponding pro-tumoural immune response supporting disease progression.

中文翻译:


PI3Kα靶向,将胰腺癌的进化消灭在萌芽状态



Thibault等人(2021) 通过证明 PI3Kα 在宏观转移性疾病的调节中的作用以及支持疾病进展的相应促肿瘤免疫反应,阐明了介导胰腺导管腺癌 (PDAC) 转移进化的关键信号传导事件。
更新日期:2021-07-07
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