Frustration at the restrictions to access prescribed cannabinoids in New Zealand has resulted in a black market of home-made cannabis-based products for medicinal use. These products are being made, and marketed illegally, by individuals calling themselves ‘Green Fairies’. The products take many forms and are being used to treat a range of illnesses and symptoms including pain, insomnia, anxiety, and seizures. Analytical extraction methods were developed to determine the cannabinoid content in a variety of matrices, principally those that are soluble in methanol and those that are soluble in hexane. An LC-MS/MS method was developed that detected THC, THCA, CBD, CBDA, CBG, CBGA, CBN, THCV, and CBC with lower detection limits around 0.001 mg of cannabinoid per gram (mg g⁻¹) of product. One hundred ‘Green Fairy’ samples have been analysed to determine the cannabinoid content, including 12 fully extracted cannabis oil (FECO) samples, 12 ethanolic tinctures, 6 vape juices, 39 oily liquids with olive oil, hemp seed oil, or medium chain triglycerides (MCT) as a base, and 31 waxy solids made using coconut oil. Nine named cannabis plant cultivars purported to be used to make these products have also been analysed. The results of the analyses show that these Green Fairy products contain a wide range of cannabinoid concentrations and the claim that a product was high in CBD was often not correct. The proposed dose size was not specified for these products, but few would provide what is considered an effective dose when compared with the administration of commercially purified cannabinoid products available by prescription. For many products the manufacturer had specified which cannabis cultivar had been used but a comparison of cannabinoid ratios showed a lack of consistency within products said to be made from the same strain. Analysis of named cannabis cultivars available showed little variation in the relative amounts of THC and CBD.

新西兰对获取规定的大麻素的限制感到沮丧，导致用于药用的自制大麻产品黑市。这些产品是由自称为“绿色仙女”的个人非法制造和销售的。该产品有多种形式，可用于治疗多种疾病和症状，包括疼痛，失眠，焦虑和癫痫发作。开发了分析提取方法来测定各种基质中的大麻素含量，主要是那些可溶于甲醇和可溶于己烷的基质。开发了一种LC-MS / MS方法，可检测出THC，THCA，CBD，CBDA，CBG，CBGA，CBN，THCV和CBC，检出限较低，约为每克0.001 mg大麻素（mg g ^-1) 的产品。已对 100 个“Green Fairy”样品进行分析以确定大麻素含量，包括 12 个完全提取的大麻油 (FECO) 样品、12 种乙醇酊剂、6 种电子烟汁、39 种含有橄榄油、大麻籽油或中链甘油三酯的油性液体(MCT) 作为基础，以及使用椰子油制成的 31 种蜡状固体。还分析了 9 种据称用于制造这些产品的大麻植物品种。分析结果表明，这些 Green Fairy 产品含有广泛的大麻素浓度，并且声称产品 CBD 含量高的说法通常是不正确的。没有为这些产品指定建议的剂量大小，但与按处方获得的商业纯化大麻素产品相比，很少有人会提供被认为是有效的剂量。对于许多产品，制造商已指定使用了哪种大麻品种，但大麻素比率的比较表明，据称由同一菌株制成的产品缺乏一致性。对可用的命名大麻品种的分析表明，四氢大麻酚和 CBD 的相对含量几乎没有变化。