Background

Epithelial ovarian cancers are a rare subset of the less than 1% of ovarian cancers diagnosed in children. This case highlights considerations when caring for these patients.

Case

Evaluation of a 12-year-old postmenarchal girl who presented with suprapubic pain revealed a solid/cystic pelvic mass involving bilateral adnexa and elevated Cancer Antigen 125 (CA-125) level. Diagnostic laparoscopy pathology confirmed low-grade papillary serous ovarian carcinoma. Treatment involved surgical tumor debulking, hysterectomy, bilateral salpingo-oophorectomy, and omentectomy; adjuvant chemotherapy with no residual disease, and normalization of Cancer Antigen 125 (CA-125) level; and an aromatase inhibitor for maintenance.

Summary and Conclusion

In children with adult-type gynecologic cancers necessitating treatments including surgical sterilization and hormone-modulating therapy, psychological support and developmentally informed collaboration between adult and pediatric services is essential. Clinical decisions for long-term bone and sexual health present opportunities for future research.

中文翻译：

---

小儿上皮性卵巢癌治疗中的多学科临床考虑

背景

在儿童诊断出的不到 1% 的卵巢癌中，上皮性卵巢癌是一个罕见的子集。这个案例突出了照顾这些患者时的注意事项。

案子

对一名出现耻骨上疼痛的 12 岁月经后女孩的评估显示，盆腔实性/囊性肿块涉及双侧附件和癌症抗原 125 (CA-125) 水平升高。诊断性腹腔镜病理证实为低级别乳头状浆液性卵巢癌。治疗包括手术切除肿瘤、子宫切除术、双侧输卵管卵巢切除术和网膜切除术；辅助化疗，无残留病灶，癌症抗原 125 (CA-125) 水平正常化；以及用于维护的芳香酶抑制剂。

总结与结论

对于患有成人型妇科癌症的儿童，需要进行手术绝育和激素调节治疗等治疗，心理支持以及成人和儿科服务之间的知情合作是必不可少的。长期骨骼和性健康的临床决策为未来的研究提供了机会。