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An FCER2 polymorphism is associated with increased oral leukotriene receptor antagonists and allergic rhinitis prescribing
Clinical & Experimental Allergy ( IF 6.3 ) Pub Date : 2021-05-29 , DOI: 10.1111/cea.13958 Patricia Soares 1 , Katy Fidler 1 , Jessie Felton 2 , Christina J Jones 3 , Roger Tavendale 4 , Anke Hövels 5 , Stephen Bremner 6 , Colin N A Palmer 4 , Somnath Mukhopadhyay 1
中文翻译:
FCER2 多态性与增加的口服白三烯受体拮抗剂和过敏性鼻炎处方有关
更新日期:2021-08-03
Clinical & Experimental Allergy ( IF 6.3 ) Pub Date : 2021-05-29 , DOI: 10.1111/cea.13958 Patricia Soares 1 , Katy Fidler 1 , Jessie Felton 2 , Christina J Jones 3 , Roger Tavendale 4 , Anke Hövels 5 , Stephen Bremner 6 , Colin N A Palmer 4 , Somnath Mukhopadhyay 1
Affiliation
Key Messages
- We explored associations between genotype and prescriptions for allergic conditions in the BREATHE cohort.
- The low-affinity IgE receptor CC genotype was associated with increased prescriptions for allergic conditions.
- Associations were not all statistically significant, and these findings need replication in another cohort study.
中文翻译:
FCER2 多态性与增加的口服白三烯受体拮抗剂和过敏性鼻炎处方有关
关键信息
- 我们在 BREATHE 队列中探索了基因型与过敏性疾病处方之间的关联。
- 低亲和力 IgE 受体 CC 基因型与过敏性疾病处方增加有关。
- 关联并非都具有统计学意义,这些发现需要在另一项队列研究中重复。