Corectopia grading: A novel classification system,Seminars in Ophthalmology

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Corectopia grading: A novel classification system
Seminars in Ophthalmology ( IF 1.9 ) Pub Date : 2021-05-29 , DOI: 10.1080/08820538.2021.1926517
Natalia Anisimova _{1,

2} , Lisa Arbisser ₃ , Argyrios Tzamalis ₄ , Beáta Éva Petrovski ₅ , Natalya Shilova ₆ , Goran Petrovski ₇ , Sergey Anisimov _{1,

2} , Boris Malyugin _{1,

6}

Affiliation

ABSTRACT

Objectives

To present and validate the novel grading system for objective classification of corectopia.

Subjects and Methods

We evaluated 28 eyes of 28 patients with or without corectopia and validated the grading and classification system for corectopia according to three major criteria: (i) direction, (ii) extent, and (iii) alteration of mydriasis. Intraclass correlation coefficient (ICC) and inter-rater agreement between 7 inexperienced and 1 experienced ophthalmologist against a golden standard (GS) were calculated.

Results

The ICC for the 7 inexperienced ophthalmologists regarding the grading of direction and centration of the pupil was 0.83 (95% confidence interval (CI), 0.74 to 0.90; p < .001) and 0.57 (95% CI, 0.43 to 0.72; p < .001), respectively. The inter-rater agreement was the same or almost the same in cases of pupil decentration between the inexperienced, experienced ophthalmologists and the GS (k = 0.82; 95% CI, 0.64–1.00; p < .001). In assessing the direction of pupil displacement, the inter-rater agreement was almost perfect between the inexperienced (k = 0.93; 95% CI, 0.84–1.00; p < .001) and experienced (k = 0.92; 95% CI: 0.82–1.02; p < .001) ophthalmologists and the GS.

Conclusion

The first detailed clinical classification is proposed for objective corectopia grading particularly relevant in documenting and assessing progressive disease. It was confirmed to be acceptable for clinical use by inexperienced and experienced ophthalmologists alike.

中文翻译：

正视眼分级：一种新的分类系统

摘要

目标

提出并验证用于核心异位客观分类的新型分级系统。

主题和方法

我们评估了 28 名患有或不患有异位症的患者的 28 只眼睛，并根据三个主要标准验证了异位症的分级和分类系统：(i) 方向，(ii) 范围，和 (iii) 散瞳的改变。计算了 7 名没有经验的眼科医生和 1 名有经验的眼科医生对黄金标准 (GS) 的组内相关系数 (ICC) 和评分者间一致性。

结果

7 名经验不足的眼科医生在瞳孔方向和中心分级方面的 ICC 为 0.83（95% 置信区间 (CI)，0.74 至 0.90；p < .001）和 0.57（95% CI，0.43 至 0.72；p < .001），分别。在没有经验的、有经验的眼科医生和 GS 之间瞳孔偏心的情况下，评估者间的一致性相同或几乎相同（k = 0.82；95% CI，0.64-1.00；p < .001）。在评估瞳孔位移方向时，无经验者 (k = 0.93; 95% CI, 0.84–1.00; p < .001) 和有经验者 (k = 0.92; 95% CI: 0.82– 1.02；p < .001) 眼科医生和 GS。