A 7-year-old male neutered Labrador Retriever dog presented with acute-onset fever, shifting limb lameness and anorexia, with development of acute respiratory distress. At necropsy, there was vegetative endocarditis, which effaced the aortic valve. Gram staining of impression smears from the aortic valve and kidney revealed numerous gram-positive rods with some coryneform bacteria. Similar coryneform bacteria were isolated on aerobic culture of the aortic valve. Identification was attempted by matrix-assisted laser desorption ionization time-of-flight mass spectrometry and 16S sequencing, the latter of which indicated Corynebacterium mustelae. This is the second reported case of endocarditis in a dog involving C. mustelae and the first with a description of post-mortem pathology. This case is an example of the utility of various modalities to identify facultative anaerobic bacterial pathogens that may be difficult to culture and may be more widespread than previously diagnosed.

一只 7 岁雄性拉布拉多犬绝育，出现急性发热、移动性肢体跛行和厌食症，并出现急性呼吸窘迫。尸检发现植物性心内膜炎，主动脉瓣消失。主动脉瓣和肾脏印模涂片革兰氏染色显示大量革兰氏阳性棒状杆菌和一些棒状细菌。在主动脉瓣的需氧培养物中分离出类似的棒状细菌。尝试通过基质辅助激光解吸电离飞行时间质谱和 16S 测序进行鉴定，后者表明是鼬棒状杆菌。这是涉及C. mustelae的狗的第二例心内膜炎报告病例第一个是对死后病理学的描述。这个案例是使用各种方法来识别兼性厌氧细菌病原体的一个例子，这些病原体可能难以培养并且可能比以前诊断的更广泛。