Cerebral radiation necrosis is the most serious late reaction to high doses of ionising radiation to the brain, and its treatment is generally unsatisfactory. We present a patient who developed cerebral radiation necrosis after protracted fluoroscopy during repeated embolisations of an extracranial arteriovenous malformation. Treatment with bevacizumab (a humanised murine monoclonal antibody against vascular endothelial growth factor) was followed by neurological and radiological improvements.

中文翻译：

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医源性脑放射坏死

脑放射坏死是对脑部高剂量电离辐射最严重的晚期反应，其治疗效果普遍不理想。我们介绍了一名患者，该患者在反复栓塞颅外动静脉畸形期间进行长时间透视后发生脑放射坏死。用贝伐单抗（一种抗血管内皮生长因子的人源化鼠单克隆抗体）治疗后，神经和放射学得到改善。