Emotional conflict adaptation involving ventral anterior cingulate cortex (ACC) suppression of the amygdala is thought to be important in emotion regulation, with evidence of impaired implicit emotion regulation in emotional distress disorders. However, it is unclear how this impairment is associated with daily-life emotion dysregulation in emotional distress disorders. In the current study, female participants with an emotional distress disorder (N = 27) were scanned with MRI while completing an implicit emotion conflict regulation task that involved identifying the facial expression of an image while ignoring an overlaid congruent or incongruent affect label. Participants then completed two weeks of ambulatory assessment of daily-life emotion dysregulation. Consistent with previous research on comorbid emotional distress disorders (Etkin and Schatzberg, 2011), there was no behavioral effect of emotional conflict adaptation (p = .701) but a significant effect of congruent adaptation (p = .006), suggesting impairment is specific to implicit emotional conflict regulation. Additionally, there was no neural evidence of emotional conflict adaptation in the ventral ACC and amygdala (ps > .766). Further, in our primary psychophysiological interactions analyses, we examined ventral ACC-amygdala functional connectivity. As hypothesized, increased ventral ACC-amygdala functional connectivity for emotional conflict adaptation was associated with increased daily-life affective instability (p = .022), but not mean daily-life negative affect (p = .372). Overall, results provide behavioral and neural evidence of impaired implicit emotional conflict adaptation in individuals with emotional distress disorders and suggests that this impairment is related to daily-life affective instability in these disorders.

涉及杏仁核腹侧前扣带皮层 (ACC) 抑制的情绪冲突适应被认为在情绪调节中很重要，有证据表明情绪困扰障碍中内隐情绪调节受损。然而，尚不清楚这种损害如何与情绪困扰障碍中的日常生活情绪失调相关。在目前的研究中，患有情绪困扰的女性参与者 ( N = 27) 在完成隐性情绪冲突调节任务的同时用 MRI 扫描，该任务涉及识别图像的面部表情，同时忽略重叠的一致或不一致的情感标签。然后，参与者完成了为期两周的日常生活情绪失调的动态评估。对伴发情绪困扰障碍（Etkin和Schatzberg，2011）先前的研究相一致，有情感冲突适应的行为没有影响（p  = 0.701），但一致的适应（的显著效果p  = 0.006），表明损害特定到隐性的情绪冲突调节。此外，在腹侧 ACC 和杏仁核中没有情绪冲突适应的神经证据（ps > .766）。此外，在我们的主要心理生理相互作用分析中，我们检查了腹侧 ACC-杏仁核功能连接。正如假设的那样，用于情绪冲突适应的腹侧 ACC-杏仁核功能连接增加与日常生活情感不稳定性增加有关 ( p  = .022)，但与日常生活负面影响 无关( p = .372)。总体而言，结果提供了情绪困扰障碍个体内隐情绪冲突适应受损的行为和神经证据，并表明这种障碍与这些障碍的日常生活情感不稳定有关。