A multidimensional group testing approach was utilised for the deconvolution of reagents for a Suzuki cross-coupling reaction. This proof of concept aimed to accelerate the identification of the best reagents for such a reaction. Two deconvolution approaches showed that K₂CO₃, ethanol and benzyldiphenylphosphine were the optimal reagents. With this approach, the optimal reagents are identified faster, and the number of reactions is drastically reduced.

Graphical Abstract

中文翻译：

---

用于 Suzuki C-C 偶联反应试剂优化的多维组测试方法

使用多维组测试方法对 Suzuki 交叉偶联反应的试剂进行解卷积。这一概念验证旨在加速确定用于此类反应的最佳试剂。两种解卷积方法表明K ₂ CO ₃、乙醇和苄基二_苯基膦是最佳试剂。使用这种方法，可以更快地确定最佳试剂，并大大减少反应次数。

图形概要