Theses reviewed in this issue include “Engineering Protein Disaggregases to Counter Alpha-Synuclein and Amyloid-Beta Neurotoxicity,” “Hyperglycaemia Induced Immunomodulation of Macrophages in Diabetic Vascular Disease,” “Microvasculature-on-a-Chip Systems for Human Disease Modeling,” “Senescence Surveillance: The Interplay Between the Immune System and Senescent Cells,” “The HMG Transcription Factor TOX Induces a Transcriptional and Epigenetic Program of CD8⁺ T Cell Exhaustion in Chronic Infection and Cancer,” and “Zero to One—Translational Advancements in the Field of Xenotransplantation.”

中文翻译：

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对最近与抗击老龄化相关的一些论文的评论：2021 年 6 月

本期综述的论文包括“工程蛋白质分解酶以对抗 α-突触核蛋白和淀粉样蛋白-β 神经毒性”、“高血糖诱导的糖尿病血管疾病巨噬细胞免疫调节”、“用于人类疾病建模的芯片微血管系统”、“衰老监测：免疫系统和衰老细胞之间的相互作用”、“HMG 转录因子 TOX在慢性感染和癌症中诱导 CD8 ⁺ T 细胞耗竭的转录和表观遗传程序”和“从零到一——该领域的翻译进展异种移植。”