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Biocompatibility of Voronoi porous structure by selective laser melting
Journal of Laser Applications ( IF 1.7 ) Pub Date : 2021-03-24 , DOI: 10.2351/7.0000185
Shoujin Zeng 1 , Qirui Wu 1 , Jianhua Ye 1 , Chuansheng Li 1 , Guang Liu 1
Affiliation  

Biocompatibility has been a major concern in the field of medical implants, and the “stress shielding” effect can be detrimental to the growth of bone cells. In this work, a parametric irregular porous structure model based on bionics design was established. The influence of different parameters on the elastic modulus, compressive strength, average pore size, and porosity was investigated. An optimization model using the grey relational analysis was established by controlling the irregularity, seed points, and strut diameter. With the goal of meeting biological requirements, the optimization results showed that the elastic modulus decreased by 40.21% and the porosity increased by 17.58%. Irregularity had little effect on the elastic modulus, porosity, and average pore size, and it was negatively correlated with compressive strength. The strut diameter and seed points were positively correlated with the elastic modulus and compressive strength but negatively correlated with the porosity and average pore size, and the seed count had the largest impact. By adjusting these parametric models, the optimization factors were obtained based on the elastic modulus, porosity, average pore size, and compressive strength of human bone. These results provide theoretical guidance for studying the mechanical properties of irregular porous structures fabricated via selective laser melting.

中文翻译:

选择性激光熔化 Voronoi 多孔结构的生物相容性

生物相容性一直是医疗植入物领域的主要问题,“应力屏蔽”效应可能不利于骨细胞的生长。在这项工作中,建立了一个基于仿生学设计的参数化不规则多孔结构模型。研究了不同参数对弹性模量、抗压强度、平均孔径和孔隙率的影响。通过控制不规则度、种子点和支柱直径,建立使用灰色关联分析的优化模型。以满足生物学要求为目标,优化结果表明,弹性模量降低了40.21%,孔隙率增加了17.58%。不规则度对弹性模量、孔隙率和平均孔径影响不大,与抗压强度呈负相关。支柱直径和种子点与弹性模量和抗压强度呈正相关,与孔隙率和平均孔径呈负相关,种子数影响最大。通过调整这些参数模型,得到基于人体骨骼弹性模量、孔隙率、平均孔径和抗压强度的优化因子。这些结果为研究通过选择性激光熔化制造的不规则多孔结构的机械性能提供了理论指导。优化因素是根据人体骨骼的弹性模量、孔隙率、平均孔径和抗压强度获得的。这些结果为研究通过选择性激光熔化制造的不规则多孔结构的机械性能提供了理论指导。优化因素是根据人体骨骼的弹性模量、孔隙率、平均孔径和抗压强度获得的。这些结果为研究通过选择性激光熔化制造的不规则多孔结构的机械性能提供了理论指导。
更新日期:2021-05-28
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