The present study was conducted to evaluate the efficacy of combinations of organic, inorganic acidifier and essential oil blends on growth performance and intestinal health of broilers. A total of 1,200 Vencobb 400 male and female chicks were randomly distributed to 6 treatment groups with 10 replicates of 20 birds each. Treatments groups were Control (C) without acidifier, combination of inorganic acid/organic acids (T1), combinations of organic acids (T2), combination of organic acids and essential oil (T3), combination of organic acids and medium chain fatty acids (T4) and double salted organic acid (T5). Corn-soybean diet supplemented with 5% meat and bone meal was fed to provoke challenges on intestinal health conditions. Body weight gain, feed intake, feed conversion ratio, and livability were measured until 42 d on weekly basis. On d 42, intestinal lesion scoring and ileal microbial populations of birds (Total coliforms, Clostridium perfringens, lactic acid bacteria) were assessed. On d 42, combination of organic acids (T2) and organic acids with essential oil (T3) had shown significantly improved body weight and average daily gain over control (C) (P < 0.05). Combination of organic acids (T2) also showed significantly improved feed conversion by 5 points over control (P < 0.05). In terms of microbiological parameters, all the treatments except T5 had shown significantly lower (P < 0.05) bacterial enteritis lesions and Clostridial populations, over control. Based on the outcome of trial results, combination of organic acids (T2) and combination with essential oil (T3) had shown enhanced performance with better economic return under challenged dietary conditions with animal protein source. The findings of this study shed light on the supplementation of organic acids acidifiers as an able substitute to improve the performance of broilers without the use of feed antibiotics.

本研究旨在评估有机、无机酸化剂和精油混合物的组合对肉鸡生长性能和肠道健康的功效。总共 1,200 只 Vencobb 400 雄性和雌性小鸡被随机分配到 6 个处理组，每组 20 只鸡 10 个重复。处理组为不含酸化剂的对照组（C）、无机酸/有机酸的组合（T1）、有机酸的组合（T2）、有机酸和精油的组合（T3）、有机酸和中链脂肪酸的组合（ T4) 和复盐有机酸 (T5)。玉米-大豆饮食补充了 5% 的肉和骨粉，以激发对肠道健康状况的挑战。每周测量体重增加、采食量、饲料转化率和存活率，直到 42 天。在第 42 天，评估了总大肠菌群、产气荚膜梭菌、乳酸菌）。在第 42 天，有机酸 (T2) 和有机酸与精油 (T3) 的组合显示出比对照 (C) 显着改善的体重和平均每日增重 ( P < 0.05)。有机酸的组合 (T2) 也显示比对照显着提高饲料转化率 5 个百分点 ( P < 0.05)。在微生物学参数方面，除 T5 外，所有处理均显示显着降低（P < 0.05）细菌性肠炎病变和梭菌人口，过度控制。根据试验结果，有机酸组合 (T2) 和精油组合 (T3) 在具有动物蛋白来源的挑战饮食条件下表现出增强的性能和更好的经济回报。本研究的结果阐明了添加有机酸酸化剂作为一种能够在不使用饲料抗生素的情况下提高肉鸡生产性能的替代品。