当前位置: X-MOL 学术J. Antibiot. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis
The Journal of Antibiotics ( IF 2.1 ) Pub Date : 2021-05-27 , DOI: 10.1038/s41429-021-00426-1
Lee Su Ha 1 , Dae-Won Ki 1 , Ji-Yul Kim 1 , Dae-Cheol Choi 1 , In-Kyoung Lee 1 , Bong-Sik Yun 1
Affiliation  

In our effort to find antimicrobial agents from higher fungi, we isolated a new compound, dentipellin (1), along with three known glycosylated diterpenes, erinacines A-C (2-4) from culture broth of Dentipellis fragilis. Their chemical structures were determined by spectroscopic methods including NMR and mass measurements. These compounds exhibited weak antibacterial and antifungal activities.



中文翻译:

Dentipellin,一种来自脆弱牙床菌培养液的新型抗生素

在我们从高等真菌中寻找抗微生物剂的努力中,我们从脆弱齿牙菌的培养液中分离了一种新化合物牙菌素 ( 1 ),以及三种已知的糖基化二萜、鼠尾草酸 AC ( 2-4 ) 。它们的化学结构是通过光谱方法确定的,包括核磁共振和质量测量。这些化合物表现出弱的抗菌和抗真菌活性。

更新日期:2021-05-27
down
wechat
bug