Cerebral polymer coating embolism from intravascular devices represents a potentially serious complication to endovascular therapy (EVT). We report two cases of neuroendovascular treatment where filamentous polymer fragments were noted possibly due to damage of the surface coating during manipulation and backloading of microguidewires. As the exact origin of the debris was initially not known, microguidewires and fragments were examined with light microscopy, stereomicroscopy, scanning electron microscopy and attenuated-total-reflection Fourier transform infrared spectroscopy. Fragments consisted of polytetrafluoroethylene and silicone oil stemming from the proximal shaft of a standard microguidewire. To our knowledge, this is the first report of polytetrafluoroethylene coating fragments created during EVT. Future studies should assess the mechanism of polymer coating delamination and its potential consequences during EVT including inadvertent fragment migration into the cerebral circulation.

来自血管内装置的脑聚合物涂层栓塞是血管内治疗 (EVT) 潜在的严重并发症。我们报告了两例神经血管内治疗病例，其中注意到丝状聚合物碎片可能是由于微导丝的操作和回载过程中表面涂层的损坏。由于最初不知道碎片的确切来源，因此用光学显微镜、立体显微镜、扫描电子显微镜和衰减全反射傅里叶变换红外光谱检查了微导丝和碎片。碎片由来自标准微导丝近端轴的聚四氟乙烯和硅油组成。据我们所知，这是首次报道 EVT 期间产生的聚四氟乙烯涂层碎片。