A 33-year-old man with a history of chronic toluene abuse through glue sniffing, developed tremors, cerebellar signs and cognitive decline. MR scan of the brain showed global cerebral and cerebellar atrophy with symmetrical T2-weighted hypointensities in the basal ganglia, thalami and midbrain. After stopping glue sniffing, his tremors, ataxia of gait, speech and cognition partially improved. Early recognition and intervention of toluene-induced leukodystrophy could prevent ongoing morbidity and premature mortality.

中文翻译：

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由嗅探胶引起的甲苯引起的脑白质营养不良

一名 33 岁的男子有通过嗅探胶水长期滥用甲苯的病史，出现震颤、小脑体征和认知能力下降。脑部 MR 扫描显示全脑和小脑萎缩，基底节、丘脑和中脑对称性 T2 加权低信号。停止吸胶后，他的颤抖、步态共济失调、言语和认知部分得到改善。早期识别和干预甲苯引起的脑白质营养不良可以预防持续的发病率和过早死亡。