This study aimed to assess the association of childhood trauma, stressful life events and HIV stigma with mental health in South African adolescents from the Cape Town Adolescent Antiretroviral Cohort (CTAAC). The Childhood Trauma Questionnaire, Life Events Questionnaire and the HIV Stigma Scale for South African Adolescents Living with HIV was used to assess childhood trauma, stressful life events and stigma in adolescents living with perinatally acquired HIV and healthy controls enrolled in the CTAAC. These measures were associated with mental health outcomes including the Beck-Youth Inventories, Child Behaviour Checklist, Columbian Impairment Scale, Childrens Motivation Scale, Conners Scale for Attention Deficit Hyperactivity Disorder using Pearson correlations and self-reported alcohol use, using Spearman-rank correlation. 63.7% of adolescents reported at least one childhood trauma on the CTQ. Significant associations were reported between CTQ measures and Beck-Youth Inventories. Emotional abuse was associated with anxiety, anger, depression and disruptive behaviour. Emotional neglect was associated with poor self-concept and disruptive behaviour. LEQ total score was significantly associated with Beck-Youth Inventories including anxiety, depression, anger and disruptive behaviour scales. HIV stigma was significantly associated with Beck-Youth Inventories including depression, anger and disruptive behaviour. Childhood trauma, stressful life events and HIV stigma in South African adolescents are associated with anxiety, depression, anger, disruptive-behaviour and poor self-concept. This study highlights the importance of enquiring about exposure to a variety of traumas, particularly those commonly experienced by South African adolescents. In addition, it is important to understand the impact of trauma exposure on each individuals mental health and functioning.

本研究旨在评估来自开普敦青少年抗逆转录病毒队列 (CTAAC) 的南非青少年的童年创伤、压力性生活事件和 HIV 耻辱感与心理健康之间的关系。儿童创伤问卷、生活事件问卷和针对感染 HIV 的南非青少年的 HIV 污名量表用于评估感染围产期获得性 HIV 的青少年的童年创伤、压力性生活事件和污名以及参加 CTAAC 的健康对照。这些措施与心理健康结果相关，包括使用 Pearson 相关性的 Beck-Youth Inventories、儿童行为清单、Columbian Impairment 量表、儿童动机量表、Conners 注意力缺陷多动障碍量表和使用 Spearman 等级相关性的自我报告酒精使用量表。63. 7% 的青少年在 CTQ 中报告了至少一次童年创伤。据报道，CTQ 措施与 Beck-Youth 清单之间存在显着关联。情感虐待与焦虑、愤怒、抑郁和破坏性行为有关。情感忽视与自我概念差和破坏性行为有关。LEQ 总分与 Beck-Youth 量表显着相关，包括焦虑、抑郁、愤怒和破坏性行为量表。艾滋病毒耻辱与贝克青年量表显着相关，包括抑郁、愤怒和破坏性行为。南非青少年的童年创伤、压力性生活事件和 HIV 耻辱与焦虑、抑郁、愤怒、破坏性行为和自我概念差有关。这项研究强调了询问暴露于各种创伤的重要性，尤其是南非青少年普遍经历的那些。此外，重要的是要了解创伤暴露对每个人的心理健康和功能的影响。