Background: Cystatin C (CSTC), a cysteine protease inhibitor, is found to be elevated in periodontal disease in an attempt to counterbalance the proteolytic enzymes and increased osteoclastic activity. Evidence on CSTC levels in periodontal health and disease has reported contradicting results, making its role as a biomarker in periodontal pathogenesis inconclusive.

中文翻译：

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CST3基因与其蛋白的关联：胱抑素C在健康和严重牙周病中的作用

背景：胱抑素 C (CSTC) 是一种半胱氨酸蛋白酶抑制剂，被发现在牙周病中升高，以试图平衡蛋白水解酶和增加的破骨细胞活性。牙周健康和疾病中 CSTC 水平的证据报告了相互矛盾的结果，使其作为牙周发病机制中的生物标志物的作用尚无定论。