Soft tissue sarcomas of the foot are extremely rare and can therefore be misdiagnosed as benign diseases, and be prematurely removed with an unplanned excision. The standard treatment is a wide local excision with an addition of radiotherapy as an alternative to a radical resection (e.g., below-knee or foot amputation). We report on a patient with primary malignant peripheral nerve sheath tumor in the foot plantar soft tissue, who had no evidence of the disease and no severe late toxicity higher than grade 2, 40 months after receiving amputation of toes and adjuvant interstitial high-dose-rate brachytherapy (HDR-BT). To the best of our knowledge, only a few cases were treated with HDR-BT with this scenario. From our findings, HDR-BT could be a safe and quick treatment option for these types of lesions.

中文翻译：

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足部恶性周围神经鞘瘤的辅助大剂量间质近距离放射治疗一例

足部软组织肉瘤极为罕见，因此可能会被误诊为良性疾病，并且未经计划切除会过早切除。标准治疗是广泛的局部切除术，除了放疗以外，还可以进行根治性切除术（例如，膝盖以下或脚截肢）。我们报道了一位在足底软组织中患有原发性恶性周围神经鞘瘤的患者，该患者在接受脚趾截肢和辅助性间质性大剂量药物治疗后40个月没有该病的证据，并且没有高于2级的严重晚期毒性。率近距离放射疗法（HDR-BT）。据我们所知，在这种情况下，只有少数病例接受了HDR-BT的治疗。根据我们的发现，HDR-BT对于这些类型的病变可能是一种安全，快速的治疗选择。