Background: Alzheimer's disease (AD) is the most common form of dementia with genetic and environmental risk contributing to its development. Graph theoretical analyses of brain networks constructed from structural and functional magnetic resonance imaging (MRI) measurements have identified connectivity changes in AD and individuals with mild cognitive impairment. However, brain connectivity in asymptomatic individuals at risk of AD remains poorly understood.

中文翻译：

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痴呆症风险因素会改变中心，但在无症状个体中保持其他连通性指标不变：图表理论分析

背景：阿尔茨海默病 (AD) 是最常见的痴呆形式，其发展具有遗传和环境风险。从结构和功能磁共振成像 (MRI) 测量构建的大脑网络的图形理论分析已经确定了 AD 和轻度认知障碍个体的连通性变化。然而，对于有 AD 风险的无症状个体的大脑连通性仍然知之甚少。