Background: Alzheimer's disease (AD) is the most common form of dementia with genetic and environmental risk contributing to its development. Graph theoretical analyses of brain networks constructed from structural and functional magnetic resonance imaging (MRI) measurements have identified connectivity changes in AD and individuals with mild cognitive impairment. However, brain connectivity in asymptomatic individuals at risk of AD remains poorly understood.

中文翻译：

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痴呆症风险因素改变了无症状个体的中枢但保持其他连接性指标不变：图论分析


背景：阿尔茨海默病（AD）是最常见的痴呆症，遗传和环境风险导致其发生。对根据结构和功能磁共振成像 (MRI) 测量构建的大脑网络进行图论分析，发现了 AD 和患有轻度认知障碍的个体的连接变化。然而，对于有 AD 风险的无症状个体的大脑连接仍然知之甚少。