In this paper, we have developed a graphene oxide/Au@Ag nanobones membrane (GO/Au@Ag NBs membrane) for simultaneous enrichment and SERS detection of colorants in beverages. Raman enhancement effect of Au@Ag nanobones (NBs) and enrichment capability of graphene oxide (GO) are contributed to the high sensitivity of GO/Au@Ag NBs membrane. Microporous membrane provides a support template for uniformly loading high-density GO/Au@Ag NBs. When beverage flow through the portable filtration unit with GO/Au@Ag NBs membrane, colorant molecules could be efficiently enriched. The prepared GO/Au@Ag NBs membrane exhibits an excellent sensitivity with a LOD of Rhodamine 6 G at 1.12 × 10⁻⁹ mol/L, and has good performances of uniformity (with an RSD of 7.87 %), repeatability (with an RSD of 10.44 %), time stability (stored up to 60 days). Six types of colorants were sensitively detected combined with GO/Au@Ag NBs membranes, portable filtration unit and self-development portable Raman system. The lowest distinguished amounts of molecular accumulation are well below the maximum usage limits and the limits of visual recognition. Support vector machine model was established to identify the types of colorants, including colorants with coincident Raman peaks or similar visual colors, with an average accuracy of 94.8 %. In addition, GO/Au@Ag NBs membranes were used to enrich and detect colorant additives in commercial beverages, brilliant blue in energy beverage and carmine in bayberry wine were successfully detected. These results indicate GO/Au@Ag NBs membranes combined with a portable filtration unit can effectively enrich and rapidly detect colorants in beverages, and has great potential in the field of on-site and sensitive food safety detection.

在本文中，我们开发了一种氧化石墨烯/Au@Ag 纳米骨膜（GO/Au@Ag NBs 膜），用于饮料中着色剂的同时富集和 SERS 检测。Au@Ag纳米骨（NBs）的拉曼增强效应和氧化石墨烯（GO）的富集能力有助于GO/Au@Ag NBs膜的高灵敏度。微孔膜为均匀加载高密度 GO/Au@Ag NBs 提供了支撑模板。当饮料流过带有 GO/Au@Ag NBs 膜的便携式过滤装置时，可以有效地富集着色剂分子。制备的 GO/Au@Ag NBs 膜表现出优异的灵敏度，罗丹明 6 G 的 LOD 为 1.12 × 10 ^-9mol/L，具有良好的均一性（RSD 7.87%）、重复性（RSD 10.44%）、时间稳定性（可保存60天）。结合GO/Au@Ag NBs膜、便携式过滤装置和自行开发的便携式拉曼系统，对六种着色剂进行了灵敏检测。分子积累的最低显着量远低于最大使用限制和视觉识别限制。建立支持向量机模型来识别着色剂的类型，包括具有重合拉曼峰或相似视觉颜色的着色剂，平均准确率为94.8%。此外，使用GO/Au@Ag NBs膜富集和检测商业饮料中的着色剂添加剂，成功检测了能量饮料中的亮蓝和杨梅酒中的胭脂红。