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The α2δ-1/NMDA receptor complex is involved in brain injury after intracerebral hemorrhage in mice
Annals of Clinical and Translational Neurology ( IF 4.4 ) Pub Date : 2021-05-25 , DOI: 10.1002/acn3.51372
Jingchen Li 1 , Guoqiang Song 1 , Qianxu Jin 1 , Liqiang Liu 1 , Liang Yang 1 , Yuanyu Wang 1 , Xuesong Zhang 1 , Zongmao Zhao 1
Affiliation  

Intracerebral hemorrhage (ICH), a common cerebrovascular disease, seriously threatens human health and has severe secondary injuries, while existing treatment methods have many limitations. α2δ-1 is a subunit of voltage-gated Ca2+ channels (VGCCs) and can act on glutamate receptor N-methyl-D-aspartate receptors (NMDARs) to relieve neuropathic pain.

中文翻译:

α2δ-1/NMDA受体复合物与小鼠脑出血后脑损伤有关

脑出血(ICH)是一种常见的脑血管疾病,严重威胁人类健康,具有严重的继发性损伤,而现有的治疗方法存在诸多局限性。α 2 δ -1 是电压门控 Ca 2+通道 (VGCC)的亚基,可作用于谷氨酸受体 N-甲基-D-天冬氨酸受体 (NMDAR) 以缓解神经性疼痛。
更新日期:2021-07-16
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